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Neutrophil Extracellular Trap Density Increases With Increasing Histopathological Severity of Crohn’s Disease
BACKGROUND: Intestinal neutrophil recruitment is a characteristic feature of the earliest stages of inflammatory bowel disease (IBD). Neutrophil elastase (NE) and myeloperoxidase (MPO) mediate the formation of neutrophil extracellular traps (NETs); NETs produce the bactericidal oxidant hypochlorous...
Autores principales: | Schroder, Angie L, Chami, Belal, Liu, Yuyang, Doyle, Chloe M, El Kazzi, Mary, Ahlenstiel, Golo, Ahmad, Gulfam, Pathma-Nathan, Nimalan, Collins, Geoff, Toh, James, Harman, Andrew, Byrne, Scott, Ctercteko, Grahame, Witting, Paul K |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036391/ https://www.ncbi.nlm.nih.gov/pubmed/34724042 http://dx.doi.org/10.1093/ibd/izab239 |
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