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Copper-catalyzed transformation of alkyl nitriles to N-arylacetamide using diaryliodonium salts

This work reports a simple and efficient method for the copper-catalyzed redox-neutral transformation of alkyl nitriles using eco-friendly diaryliodonium salts and leading to N-arylacetamides. The method features high efficiency, broad substrate scope and good functional group tolerance.

Detalles Bibliográficos
Autores principales: Sallio, Romain, Payard, Pierre-Adrien, Pakulski, Paweł, Diachenko, Iryna, Fabre, Indira, Berteina-Raboin, Sabine, Colas, Cyril, Ciofini, Ilaria, Grimaud, Laurence, Gillaizeau, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036411/
https://www.ncbi.nlm.nih.gov/pubmed/35481165
http://dx.doi.org/10.1039/d1ra02305e