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A Generic Strategy to Generate Bifunctional Two-in-One Antibodies by Chicken Immunization
Various formats of bispecific antibodies exist, among them Two-in-One antibodies in which each Fab arm can bind to two different antigens. Their IgG-like architecture accounts for low immunogenicity and also circumvents laborious engineering and purification steps to facilitate correct chain pairing...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036444/ https://www.ncbi.nlm.nih.gov/pubmed/35479092 http://dx.doi.org/10.3389/fimmu.2022.888838 |