Cargando…

Destabilization potential of beta sheet breaker peptides on Abeta fibril structure: an insight from molecular dynamics simulation study

Alzheimer's disease is characterized by amyloid-β aggregation. Currently, all the approved medications are to treat the symptoms but there is no clinically approved treatment for the cure or to prevent the progression of Alzheimer's disease (AD). Earlier reports suggest the use of small mo...

Descripción completa

Detalles Bibliográficos
Autores principales: Jani, Vinod, Sonavane, Uddhavesh, Joshi, Rajendra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036544/
https://www.ncbi.nlm.nih.gov/pubmed/35479797
http://dx.doi.org/10.1039/d1ra03609b