Anticancer activity of pyrimidodiazepines based on 2-chloro-4-anilinoquinazoline: synthesis, DNA binding and molecular docking

Multidrug resistance to chemotherapy is a critical health problem associated with mutation of the therapeutic target. Therefore, the development of anticancer agents remains a challenge to overcome cancer cell resistance. Herein, a new series of quinazoline-based pyrimidodiazepines 16a–g were synthe...

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Detalles Bibliográficos
Autores principales: Cuartas, Viviana, Aragón-Muriel, Alberto, Liscano, Yamil, Polo-Cerón, Dorian, Crespo-Ortiz, Maria del Pilar, Quiroga, Jairo, Abonia, Rodrigo, Insuasty, Braulio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036565/
https://www.ncbi.nlm.nih.gov/pubmed/35479808
http://dx.doi.org/10.1039/d1ra03509f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036565/
https://www.ncbi.nlm.nih.gov/pubmed/35479808
http://dx.doi.org/10.1039/d1ra03509f

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