Drug repurposing and computational modeling for discovery of inhibitors of the main protease (M(pro)) of SARS-CoV-2

The main protease (M(pro) or 3CL(pro)) is a conserved cysteine protease from the coronaviruses and started to be considered an important drug target for developing antivirals, as it produced a deadly outbreak of COVID-19. Herein, we used a combination of drug reposition and computational modeling ap...

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Detalles Bibliográficos
Autores principales: Silva, José Rogério A., Kruger, Hendrik G., Molfetta, Fábio A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036595/
https://www.ncbi.nlm.nih.gov/pubmed/35479789
http://dx.doi.org/10.1039/d1ra03956c

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036595/
https://www.ncbi.nlm.nih.gov/pubmed/35479789
http://dx.doi.org/10.1039/d1ra03956c

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