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Metal-free cascade synthesis of unsymmetrical 2-aminopyrimidines from imidazolate enaminones

A convenient metal-free synthesis of unsymmetrical 2-aminopyrimidines from imidazolate enaminones has been developed. In this procedure, various structural 2-aminopyrimidines, as well as 4,5-dihydroisoxazol-5-ols and pyrazoles were synthesized in moderate to excellent yields. A plausible mechanism w...

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Detalles Bibliográficos
Autores principales: Cui, Xue, Ma, Jianting, Zeng, Tingting, Xu, Junyu, Li, Youbin, Wang, Xuesong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036825/
https://www.ncbi.nlm.nih.gov/pubmed/35479033
http://dx.doi.org/10.1039/d1ra04319f