Baseline Mutations and Up-Regulation of PI3K-AKT Pathway Serve as Potential Indicators of Lack of Response to Neoadjuvant Chemotherapy in Stage II/III Breast Cancer

BACKGROUND: Neoadjuvant chemotherapy (NAC) has been expanded to hormone receptor (HR) positive breast cancer (BC) patients with operable disease, to increase the likelihood of breast-conserving surgery. Genomic profiling at baseline would reveal NAC response relevant genomic features and signaling p...

Descripción completa

Detalles Bibliográficos
Autores principales: Dong, Menghao, Shan, Benjie, Han, Xinghua, Zhao, Xiaotian, Wang, Fufeng, Zhu, Liuqing, Ou, Qiuxiang, Ma, Xiaopeng, Pan, Yueyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036956/
https://www.ncbi.nlm.nih.gov/pubmed/35480699
http://dx.doi.org/10.3389/fonc.2021.784985

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036956/
https://www.ncbi.nlm.nih.gov/pubmed/35480699
http://dx.doi.org/10.3389/fonc.2021.784985

Ejemplares similares