Rapid Manufacturing of Highly Cytotoxic Clinical-Grade SARS-CoV-2-specific T Cell Products Covering SARS-CoV-2 and Its Variants for Adoptive T Cell Therapy

Objectives: Evaluation of the feasibility of SARS-CoV-2-specific T cell manufacturing for adoptive T cell transfer in COVID-19 patients at risk to develop severe disease. Methods: Antiviral SARS-CoV-2-specific T cells were detected in blood of convalescent COVID-19 patients following stimulation wit...

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Detalles Bibliográficos
Autores principales: Bonifacius, Agnes, Tischer-Zimmermann, Sabine, Santamorena, Maria Michela, Mausberg, Philip, Schenk, Josephine, Koch, Stephanie, Barnstorf-Brandes, Johanna, Gödecke, Nina, Martens, Jörg, Goudeva, Lilia, Verboom, Murielle, Wittig, Jana, Maecker-Kolhoff, Britta, Baurmann, Herrad, Clark, Caren, Brauns, Olaf, Simon, Martina, Lang, Peter, Cornely, Oliver A., Hallek, Michael, Blasczyk, Rainer, Seiferling, Dominic, Köhler, Philipp, Eiz-Vesper, Britta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036989/
https://www.ncbi.nlm.nih.gov/pubmed/35480981
http://dx.doi.org/10.3389/fbioe.2022.867042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036989/
https://www.ncbi.nlm.nih.gov/pubmed/35480981
http://dx.doi.org/10.3389/fbioe.2022.867042

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