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Rapid Manufacturing of Highly Cytotoxic Clinical-Grade SARS-CoV-2-specific T Cell Products Covering SARS-CoV-2 and Its Variants for Adoptive T Cell Therapy
Objectives: Evaluation of the feasibility of SARS-CoV-2-specific T cell manufacturing for adoptive T cell transfer in COVID-19 patients at risk to develop severe disease. Methods: Antiviral SARS-CoV-2-specific T cells were detected in blood of convalescent COVID-19 patients following stimulation wit...
Autores principales: | Bonifacius, Agnes, Tischer-Zimmermann, Sabine, Santamorena, Maria Michela, Mausberg, Philip, Schenk, Josephine, Koch, Stephanie, Barnstorf-Brandes, Johanna, Gödecke, Nina, Martens, Jörg, Goudeva, Lilia, Verboom, Murielle, Wittig, Jana, Maecker-Kolhoff, Britta, Baurmann, Herrad, Clark, Caren, Brauns, Olaf, Simon, Martina, Lang, Peter, Cornely, Oliver A., Hallek, Michael, Blasczyk, Rainer, Seiferling, Dominic, Köhler, Philipp, Eiz-Vesper, Britta |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036989/ https://www.ncbi.nlm.nih.gov/pubmed/35480981 http://dx.doi.org/10.3389/fbioe.2022.867042 |
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