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The phosphorylated retinoid X receptor-α promotes diethylnitrosamine-induced hepatocarcinogenesis in mice through the activation of β-catenin signaling pathway

Previous studies have shown that phosphorylation of the retinoid X receptor-α (RXRα) is associated with the development of hepatocellular carcinoma (HCC). However, these findings were revealed using HCC cell lines that express phosphorylated-RXRα (p-RXRα) proteins; therefore, it remains unclear whet...

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Detalles Bibliográficos
Autores principales: Sakai, Hiroyasu, Yamada, Yasuhiro, Kubota, Masaya, Imai, Kenji, Shirakami, Yohei, Tomita, Hiroyuki, Hara, Akira, Shimizu, Masahito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9036992/
https://www.ncbi.nlm.nih.gov/pubmed/34668523
http://dx.doi.org/10.1093/carcin/bgab099