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Identification and in situ removal of an inhibitory intermediate to develop an efficient phytosterol bioconversion process using a cyclodextrin-resting cell system

A classically versatile steroid intermediate, 9α-hydroxyandrost-4-ene-3,17-dione (9α-OH-AD), can be obtained by phytosterol (PS) bioconversion using Mycobacterium. In this study, a cyclodextrin-resting cell reaction system with a high concentration of PS (50 g L(−1)) was used to produce 9α-OH-AD. Ho...

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Detalles Bibliográficos
Autores principales: Wang, Da, Zhang, Jian, Cao, Dan-Dan, Wang, Xuedong, Wei, Dongzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037027/
https://www.ncbi.nlm.nih.gov/pubmed/35481053
http://dx.doi.org/10.1039/d1ra02774c