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In silico Docking Analysis for Blocking JUNO‐IZUMO1 Interaction Identifies Two Small Molecules that Block in vitro Fertilization

Combined hormone drugs are the basis for orally administered contraception. However, they are associated with severe side effects that are even more impactful for women in developing countries, where resources are limited. The risk of side effects may be reduced by non-hormonal small molecules which...

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Detalles Bibliográficos
Autores principales: Stepanenko, Nataliia, Wolk, Omri, Bianchi, Enrica, Wright, Gavin James, Schachter-Safrai, Natali, Makedonski, Kiril, Ouro, Alberto, Ben-Meir, Assaf, Buganim, Yosef, Goldblum, Amiram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037035/
https://www.ncbi.nlm.nih.gov/pubmed/35478965
http://dx.doi.org/10.3389/fcell.2022.824629