Cargando…
In silico Docking Analysis for Blocking JUNO‐IZUMO1 Interaction Identifies Two Small Molecules that Block in vitro Fertilization
Combined hormone drugs are the basis for orally administered contraception. However, they are associated with severe side effects that are even more impactful for women in developing countries, where resources are limited. The risk of side effects may be reduced by non-hormonal small molecules which...
Autores principales: | Stepanenko, Nataliia, Wolk, Omri, Bianchi, Enrica, Wright, Gavin James, Schachter-Safrai, Natali, Makedonski, Kiril, Ouro, Alberto, Ben-Meir, Assaf, Buganim, Yosef, Goldblum, Amiram |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037035/ https://www.ncbi.nlm.nih.gov/pubmed/35478965 http://dx.doi.org/10.3389/fcell.2022.824629 |
Ejemplares similares
-
Izumo meets Juno: Preventing polyspermy in fertilization
por: Bianchi, Enrica, et al.
Publicado: (2014) -
Juno is the egg Izumo receptor and is essential for mammalian fertilisation
por: Bianchi, Enrica, et al.
Publicado: (2014) -
Cross-species fertilization: the hamster egg receptor, Juno, binds the human sperm ligand, Izumo1
por: Bianchi, Enrica, et al.
Publicado: (2015) -
Structural and functional insights into IZUMO1 recognition by JUNO in mammalian fertilization
por: Kato, Kazuki, et al.
Publicado: (2016) -
Izumo1 and Juno: the evolutionary origins and coevolution of essential sperm–egg binding partners
por: Grayson, Phil
Publicado: (2015)