The polyphenolic phytoalexin polydatin inhibits amyloid aggregation of recombinant human prion protein

Prion diseases involve misfolded and highly infectious aggregates of prion protein (PrP(Sc)) which forms amyloid plaques leading to fatal neurodegeneration. The absence of clinically proven therapeutics makes the discovery of effective remedial interventions a prime concern. Herein, we report novel...

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Detalles Bibliográficos
Autores principales: Sirohi, Preeti Rana, Kumari, Anchala, Admane, Nikita, Somvanshi, Pallavi, Grover, Abhinav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037109/
https://www.ncbi.nlm.nih.gov/pubmed/35479435
http://dx.doi.org/10.1039/d1ra01891d

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037109/
https://www.ncbi.nlm.nih.gov/pubmed/35479435
http://dx.doi.org/10.1039/d1ra01891d

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