Cargando…
The polyphenolic phytoalexin polydatin inhibits amyloid aggregation of recombinant human prion protein
Prion diseases involve misfolded and highly infectious aggregates of prion protein (PrP(Sc)) which forms amyloid plaques leading to fatal neurodegeneration. The absence of clinically proven therapeutics makes the discovery of effective remedial interventions a prime concern. Herein, we report novel...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037109/ https://www.ncbi.nlm.nih.gov/pubmed/35479435 http://dx.doi.org/10.1039/d1ra01891d |