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Targeting TP53-Mutated Acute Myeloid Leukemia: Research and Clinical Developments
TP53 is a key tumor suppressor gene that plays an important role in regulating apoptosis, senescence, and DNA damage repair in response to cellular stress. Although somewhat rare, TP53-mutated AML has been identified as an important molecular subgroup with a prognosis that is arguably the worst of a...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Dove
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037178/ https://www.ncbi.nlm.nih.gov/pubmed/35479302 http://dx.doi.org/10.2147/OTT.S265637 |