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Targeting TP53-Mutated Acute Myeloid Leukemia: Research and Clinical Developments

TP53 is a key tumor suppressor gene that plays an important role in regulating apoptosis, senescence, and DNA damage repair in response to cellular stress. Although somewhat rare, TP53-mutated AML has been identified as an important molecular subgroup with a prognosis that is arguably the worst of a...

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Detalles Bibliográficos
Autores principales: Granowicz, Eric M, Jonas, Brian A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037178/
https://www.ncbi.nlm.nih.gov/pubmed/35479302
http://dx.doi.org/10.2147/OTT.S265637

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