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Interactions of 2,6-substituted purines with purine nucleoside phosphorylase from Helicobacter pylori in solution and in the crystal, and the effects of these compounds on cell cultures of this bacterium

Helicobacter pylori represents a global health threat with around 50% of the world population infected. Due to the increasing number of antibiotic-resistant strains, new strategies for eradication of H. pylori are needed. In this study, we suggest purine nucleoside phosphorylase (PNP) as a possible...

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Detalles Bibliográficos
Autores principales: Narczyk, Marta, Wojtyś, Marta Ilona, Leščić Ašler, Ivana, Žinić, Biserka, Luić, Marija, Jagusztyn-Krynicka, Elżbieta Katarzyna, Štefanić, Zoran, Bzowska, Agnieszka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037209/
https://www.ncbi.nlm.nih.gov/pubmed/35437103
http://dx.doi.org/10.1080/14756366.2022.2061965