Novel 3-(6-methylpyridin-2-yl)coumarin-based chalcones as selective inhibitors of cancer-related carbonic anhydrases IX and XII endowed with anti-proliferative activity

Carbonic anhydrases (CAs) are one of the promising targets for the development of anticancer agents. CA isoforms are implicated in various physiological processes and are expressed in both normal and cancerous cells. Thus, non-isoform selective inhibitors are associated with several side effects. Co...

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Detalles Bibliográficos
Autores principales: Tawfik, Haytham O., Shaldam, Moataz A., Nocentini, Alessio, Salem, Rofaida, Almahli, Hadia, Al-Rashood, Sara T., Supuran, Claudiu T., Eldehna, Wagdy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037210/
https://www.ncbi.nlm.nih.gov/pubmed/35437108
http://dx.doi.org/10.1080/14756366.2022.2056734

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037210/
https://www.ncbi.nlm.nih.gov/pubmed/35437108
http://dx.doi.org/10.1080/14756366.2022.2056734

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