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Novel 3-(6-methylpyridin-2-yl)coumarin-based chalcones as selective inhibitors of cancer-related carbonic anhydrases IX and XII endowed with anti-proliferative activity
Carbonic anhydrases (CAs) are one of the promising targets for the development of anticancer agents. CA isoforms are implicated in various physiological processes and are expressed in both normal and cancerous cells. Thus, non-isoform selective inhibitors are associated with several side effects. Co...
Autores principales: | Tawfik, Haytham O., Shaldam, Moataz A., Nocentini, Alessio, Salem, Rofaida, Almahli, Hadia, Al-Rashood, Sara T., Supuran, Claudiu T., Eldehna, Wagdy M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037210/ https://www.ncbi.nlm.nih.gov/pubmed/35437108 http://dx.doi.org/10.1080/14756366.2022.2056734 |
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