Design, synthesis, and cytotoxic activities of isaindigotone derivatives as potential anti-gastric cancer agents

A series of novel derivatives of isaindigotone, which comes from the root of isaits indinatca Fort, were synthesised (Compound 1–26). Four human gastrointestinal cancer cells (HCT116, PANC-1, SMMC-7721, and AGS) were employed to evaluate the anti-proliferative activity. Among them, Compound 6 displa...

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Detalles Bibliográficos
Autores principales: Du, Kangjia, Ma, Wantong, Yang, Chengjie, Zhou, Zhongkun, Hu, Shujian, Tian, Yanan, Zhang, Hao, Ma, Yunhao, Jiang, Xinrong, Zhu, Hongmei, Liu, Huanxiang, Chen, Peng, Liu, Yingqian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037217/
https://www.ncbi.nlm.nih.gov/pubmed/35450499
http://dx.doi.org/10.1080/14756366.2022.2065672

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037217/
https://www.ncbi.nlm.nih.gov/pubmed/35450499
http://dx.doi.org/10.1080/14756366.2022.2065672

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