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Hypoxic pretreatment of adipose-derived stem cell exosomes improved cognition by delivery of circ-Epc1 and shifting microglial M1/M2 polarization in an Alzheimer’s disease mice model

Alzheimer’s disease (AD) is the most common dementia in the world. Increasing evidence has shown that exosomes from hypoxic pretreated adipose-derived stem cells (ADSCs) could be an effective cognitive function therapeutic in AD-associated pathophysiology. However, their role and regulatory mechanis...

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Detalles Bibliográficos
Autores principales: Liu, Haining, Jin, Mingming, Ji, Minxiu, Zhang, Wei, Liu, An, Wang, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037259/
https://www.ncbi.nlm.nih.gov/pubmed/35366241
http://dx.doi.org/10.18632/aging.203989