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Cholesterol-induced leucine aminopeptidase 3 (LAP3) upregulation inhibits cell autophagy in pathogenesis of NAFLD

Objectives: Leucine aminopeptidase 3 (LAP3), an M1 member of leucine aminopeptidase, was reported to be significantly upregulated in serum of nonalcoholic fatty liver disease (NAFLD) patients. However, the underlying mechanisms of LAP3 in NAFLD pathogenesis are still unknown. We aim to investigate t...

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Detalles Bibliográficos
Autores principales: Feng, Lina, Chen, Yanping, Xu, Ke, Li, Yingchao, Riaz, Farooq, Lu, Kaikai, Chen, Qian, Du, Xiaojuan, Wu, Litao, Cao, Dan, Li, Chunyan, Lu, Shemin, Li, Dongmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037261/
https://www.ncbi.nlm.nih.gov/pubmed/35404840
http://dx.doi.org/10.18632/aging.204011