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Alpha-7 Nicotinic Receptor Dampens Murine Osteoblastic Response to Inflammation and Age-Related Osteoarthritis

INTRODUCTION: Osteoarthritis (OA) is a whole-joint disease characterized by a low-grade inflammation that is involved in both cartilage degradation and subchondral bone remodeling. Since subchondral bone has a cholinergic innervation and that acetylcholine (Ach) might have an anti-inflammatory effec...

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Detalles Bibliográficos
Autores principales: Courties, Alice, Petit, Juliette, Do, Ariane, Legris, Manon, Kouki, Inès, Pigenet, Audrey, Sacitharan, Pradeep K., Ehkirch, Francois-Paul, Berenbaum, Francis, Sellam, Jérémie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037377/
https://www.ncbi.nlm.nih.gov/pubmed/35479080
http://dx.doi.org/10.3389/fimmu.2022.842538