Tumor-associated macrophages promote intratumoral conversion of conventional CD4(+) T cells into regulatory T cells via PD-1 signalling

While regulatory T cells (T(regs)) and macrophages have been recognized as key orchestrators of cancer-associated immunosuppression, their cellular crosstalk within tumors has been poorly characterized. Here, using spontaneous models for breast cancer, we demonstrate that tumor-associated macrophage...

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Detalles Bibliográficos
Autores principales: Kos, Kevin, Salvagno, Camilla, Wellenstein, Max D., Aslam, Muhammad A., Meijer, Denize A., Hau, Cheei-Sing, Vrijland, Kim, Kaldenbach, Daphne, Raeven, Elisabeth A.M., Schmittnaegel, Martina, Ries, Carola H., de Visser, Karin E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037432/
https://www.ncbi.nlm.nih.gov/pubmed/35481289
http://dx.doi.org/10.1080/2162402X.2022.2063225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037432/
https://www.ncbi.nlm.nih.gov/pubmed/35481289
http://dx.doi.org/10.1080/2162402X.2022.2063225

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