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TRIM44 links the UPS to SQSTM1/p62-dependent aggrephagy and removing misfolded proteins
Until recently, the ubiquitin-proteasome system (UPS) and macroautophagy/autophagy were considered to be two independent systems that target proteins for degradation by proteasomes or via lysosomes, respectively. Here, we report that TRIM44 (tripartite motif containing 44) is a novel link that conne...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037492/ https://www.ncbi.nlm.nih.gov/pubmed/34382902 http://dx.doi.org/10.1080/15548627.2021.1956105 |