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The eIg technology to generate Ig-like bispecific antibodies

Bispecific antibodies have emerged as therapeutic molecules with a multitude of modes of action and applications. Here, we present a novel approach to solve the light-chain problem for the generation of bispecific Ig-like antibodies using the second constant domain of IgE (EHD2) genetically modified...

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Detalles Bibliográficos
Autores principales: Kühl, Lennart, Aschmoneit, Nadine, Kontermann, Roland E., Seifert, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037507/
https://www.ncbi.nlm.nih.gov/pubmed/35427197
http://dx.doi.org/10.1080/19420862.2022.2063043