Cargando…

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy

Depolarized mitochondria can be degraded via mitophagy, a selective form of autophagy. The RAB GTPase RAB7A was recently shown to play a key role in this process. RAB7A regulates late endocytic trafficking under normal growth conditions but is translocated to the mitochondrial surface following depo...

Descripción completa

Detalles Bibliográficos
Autores principales: Yan, Bing-Ru, Li, Taoyingnan, Coyaud, Etienne, Laurent, Estelle M. N., St-Germain, Jonathan, Zhou, Yuhuan, Kim, Peter K., Raught, Brian, Brumell, John H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037554/
https://www.ncbi.nlm.nih.gov/pubmed/34432599
http://dx.doi.org/10.1080/15548627.2021.1960116