LPM3770277, a Potent Novel CDK4/6 Degrader, Exerts Antitumor Effect Against Triple-Negative Breast Cancer

Triple negative breast cancer (TNBC) is a subtype of breast cancer with significant malignancy and poor prognosis but effective treatments are limited. Given the critical role of CDK4/6 in cell cycle and the apparent success of CDK4/6 inhibitors against certain cancer, this study attempted to utiliz...

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Detalles Bibliográficos
Autores principales: Qiu, Jiahao, Bai, Xinfa, Zhang, Wenjing, Ma, Mingxu, Wang, Wenyan, Liang, Ye, Wang, Hongbo, Tian, Jingwei, Yu, Pengfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037595/
https://www.ncbi.nlm.nih.gov/pubmed/35479314
http://dx.doi.org/10.3389/fphar.2022.853993

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037595/
https://www.ncbi.nlm.nih.gov/pubmed/35479314
http://dx.doi.org/10.3389/fphar.2022.853993

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