Computational Investigation of Bending Properties of RNA AUUCU, CCUG, CAG, and CUG Repeat Expansions Associated With Neuromuscular Disorders

Expansions of RNA AUUCU, CCUG, CAG, and CUG repeats cause spinocerebellar ataxia type 10, myotonic dystrophy type 2, Huntington’s disease, and myotonic dystrophy type 1, respectively. By performing extensive molecular dynamic simulations, we investigated the bending propensities and conformational l...

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Detalles Bibliográficos
Autores principales: Taghavi, Amirhossein, Yildirim, Ilyas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037632/
https://www.ncbi.nlm.nih.gov/pubmed/35480881
http://dx.doi.org/10.3389/fmolb.2022.830161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037632/
https://www.ncbi.nlm.nih.gov/pubmed/35480881
http://dx.doi.org/10.3389/fmolb.2022.830161

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