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Palladium-catalyzed dehydrogenative C–H cyclization for isoindolinone synthesis

In this paper Pd-catalyzed intramolecular dehydrogenative C(sp(3))–H amidation for the synthesis of isoindolinones is described. This method features the use of a Pd/C catalyst and the addition of a stoichiometric amount of oxidant is not necessary. A mechanistic study suggested the possible formati...

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Detalles Bibliográficos
Autores principales: Abe, Masahiro, Ueta, Kaho, Tanaka, Saki, Kimachi, Tetsutaro, Inamoto, Kiyofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037686/
https://www.ncbi.nlm.nih.gov/pubmed/35479970
http://dx.doi.org/10.1039/d1ra04661f