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Phylogenetic analysis of migration, differentiation, and class switching in B cells

B cells undergo rapid mutation and selection for antibody binding affinity when producing antibodies capable of neutralizing pathogens. This evolutionary process can be intermixed with migration between tissues, differentiation between cellular subsets, and switching between functional isotypes. B c...

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Detalles Bibliográficos
Autores principales: Hoehn, Kenneth B., Pybus, Oliver G., Kleinstein, Steven H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037912/
https://www.ncbi.nlm.nih.gov/pubmed/35468128
http://dx.doi.org/10.1371/journal.pcbi.1009885