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The C-terminal domain of Hsp70 is responsible for paralog-specific regulation of ribonucleotide reductase

The Hsp70 family of molecular chaperones is well-conserved and expressed in all organisms. In budding yeast, cells express four highly similar cytosolic Hsp70s Ssa1, 2, 3 and 4 which arose from gene duplication. Ssa1 and 2 are constitutively expressed while Ssa3 and 4 are induced upon heat shock. Re...

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Detalles Bibliográficos
Autores principales: Knighton, Laura E., Nitika, Omkar, Siddhi, Truman, Andrew W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037926/
https://www.ncbi.nlm.nih.gov/pubmed/35417483
http://dx.doi.org/10.1371/journal.pgen.1010079