Compromised DNA Repair Promotes the Accumulation of Regulatory T Cells With an Aging-Related Phenotype and Responsiveness

Decline of immune function during aging has in part been ascribed to the accumulation of regulatory T cells (Tregs) and decreased T-cell responses with age. Aside from changes to T cells that occur over a lifetime, the impact of intracellular aging processes such as compromised DNA repair on T cells...

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Detalles Bibliográficos
Autores principales: Pieren, Daan K. J., Smits, Noortje A. M., Imholz, Sandra, Nagarajah, Bhawani, van Oostrom, Conny T., Brandt, Renata M. C., Vermeij, Wilbert P., Dollé, Martijn E. T., Guichelaar, Teun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Aging
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037984/
https://www.ncbi.nlm.nih.gov/pubmed/35474946
http://dx.doi.org/10.3389/fragi.2021.667193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9037984/
https://www.ncbi.nlm.nih.gov/pubmed/35474946
http://dx.doi.org/10.3389/fragi.2021.667193

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