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Synthesis of xanthohumol and xanthohumol-d(3) from naringenin
A six-step synthesis of xanthohumol (1a) and its d(3)-derivative (1b) from easily accessible naringenin is reported. The prenyl side chain was introduced by Mitsunobu reaction followed by the europium-catalyzed Claisen rearrangement and base-mediated opening of chromanone gave access to an α,β-conju...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society of Chemistry
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9038150/ https://www.ncbi.nlm.nih.gov/pubmed/35478583 http://dx.doi.org/10.1039/d1ra05443k |