KRP-203 Is a Desirable Immunomodulator for Islet Allotransplantation

BACKGROUND. The current standard immunosuppressive regimens, calcineurin inhibitors, have diabetogenic and anti-vascularization effects on islet grafts. KRP-203, a sphingosine-1-phosphate functional antagonist, exerts its immunomodulatory function through lymphocyte sequestration. However, the effec...

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Detalles Bibliográficos
Autores principales: Fathi, Ibrahim, Nishimura, Ryuichi, Imura, Takehiro, Inagaki, Akiko, Kanai, Norifumi, Ushiyama, Akira, Kikuchi, Masafumi, Maekawa, Masamitsu, Yamaguchi, Hiroaki, Goto, Masafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Original Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9038237/
https://www.ncbi.nlm.nih.gov/pubmed/34241985
http://dx.doi.org/10.1097/TP.0000000000003870

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9038237/
https://www.ncbi.nlm.nih.gov/pubmed/34241985
http://dx.doi.org/10.1097/TP.0000000000003870

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