Infection with the enteric pathogen C. rodentium promotes islet-specific autoimmunity by activating a lymphatic route from the gut to pancreatic lymph node

In nonobese diabetic (NOD) mice, C. rodentium promotes priming of islet-specific T-cells in pancreatic lymph nodes (PaLN), which is a critical step in initiation and perpetuation of islet-autoimmunity. To investigate mechanisms by which C. rodentium promotes T-cell priming in PaLN, we used fluoresce...

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Detalles Bibliográficos
Autores principales: Pöysti, Sakari, Toivonen, Raine, Takeda, Akira, Silojärvi, Satu, Yatkin, Emrah, Miyasaka, Masayuki, Hänninen, Arno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9038524/
https://www.ncbi.nlm.nih.gov/pubmed/35140345
http://dx.doi.org/10.1038/s41385-022-00490-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9038524/
https://www.ncbi.nlm.nih.gov/pubmed/35140345
http://dx.doi.org/10.1038/s41385-022-00490-2

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