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Combined metabolomic and transcriptomic profiling approaches reveal the cardiac response to high-fat diet

The response of vital organs to different types of nutrition or diet is a fundamental question in physiology. We examined the cardiac response to 4 weeks of high-fat diet in mice, measuring cardiac metabolites and mRNA. Metabolomics showed dramatic differences after a high-fat diet, including increa...

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Detalles Bibliográficos
Autores principales: Joseph, Leroy C., Shi, Jianting, Nguyen, Quynh N., Pensiero, Victoria, Goulbourne, Chris, Bauer, Robert C., Zhang, Hanrui, Morrow, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9038541/
https://www.ncbi.nlm.nih.gov/pubmed/35494220
http://dx.doi.org/10.1016/j.isci.2022.104184