Cargando…
PRKDC promotes hepatitis B virus transcription through enhancing the binding of RNA Pol II to cccDNA
Hepatitis B virus infection remains a major health problem worldwide due to its high risk of liver failure and hepatocellular carcinoma. Covalently closed circular DNA (cccDNA), which is present as an individual minichromosome, serves as the template for transcription of all viral RNAs and pla ays c...
Autores principales: | , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9038722/ https://www.ncbi.nlm.nih.gov/pubmed/35468873 http://dx.doi.org/10.1038/s41419-022-04852-3 |