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PRKDC promotes hepatitis B virus transcription through enhancing the binding of RNA Pol II to cccDNA

Hepatitis B virus infection remains a major health problem worldwide due to its high risk of liver failure and hepatocellular carcinoma. Covalently closed circular DNA (cccDNA), which is present as an individual minichromosome, serves as the template for transcription of all viral RNAs and pla ays c...

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Detalles Bibliográficos
Autores principales:	Fan, Yao, Liang, Yi, Liu, Yu, Fan, Hui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9038722/ https://www.ncbi.nlm.nih.gov/pubmed/35468873 http://dx.doi.org/10.1038/s41419-022-04852-3

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