Antiapoptotic Protein FAIM2 is targeted by miR-3202, and DUX4 via TRIM21, leading to cell death and defective myogenesis

Inappropriate expression of DUX4, a transcription factor that induces cell death at high levels of expression and impairs myoblast differentiation at low levels of expression, leads to the development of facioscapulohumeral muscular dystrophy (FSHD), however, the pathological mechanisms downstream o...

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Detalles Bibliográficos
Autores principales: Soliman, Hossam A. N., Toso, Erik A., Darwish, Inas E., Ali, Samia M., Kyba, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9038730/
https://www.ncbi.nlm.nih.gov/pubmed/35468884
http://dx.doi.org/10.1038/s41419-022-04804-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9038730/
https://www.ncbi.nlm.nih.gov/pubmed/35468884
http://dx.doi.org/10.1038/s41419-022-04804-x

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