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Customized bioreactor enables the production of 3D diaphragmatic constructs influencing matrix remodeling and fibroblast overgrowth

The production of skeletal muscle constructs useful for replacing large defects in vivo, such as in congenital diaphragmatic hernia (CDH), is still considered a challenge. The standard application of prosthetic material presents major limitations, such as hernia recurrences in a remarkable number of...

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Detalles Bibliográficos
Autores principales: Maghin, Edoardo, Carraro, Eugenia, Boso, Daniele, Dedja, Arben, Giagante, Mattia, Caccin, Paola, Barna, Raluca Ana-Maria, Bresolin, Silvia, Cani, Alice, Borile, Giulia, Sandrin, Deborah, Romanato, Filippo, Cecchinato, Francesca, Urciuolo, Anna, Sandonà, Dorianna, De Coppi, Paolo, Pavan, Piero G., Piccoli, Martina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9038738/
https://www.ncbi.nlm.nih.gov/pubmed/35468920
http://dx.doi.org/10.1038/s41536-022-00222-x