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Human gut-microbiome-derived propionate coordinates proteasomal degradation via HECTD2 upregulation to target EHMT2 in colorectal cancer

The human microbiome plays an essential role in the human immune system, food digestion, and protection from harmful bacteria by colonizing the human intestine. Recently, although the human microbiome affects colorectal cancer (CRC) treatment, the mode of action between the microbiome and CRC remain...

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Detalles Bibliográficos
Autores principales: Ryu, Tae Young, Kim, Kwangho, Han, Tae-Su, Lee, Mi-Ok, Lee, Jinkwon, Choi, Jinhyeon, Jung, Kwang Bo, Jeong, Eun-Jeong, An, Da Mi, Jung, Cho-Rok, Lim, Jung Hwa, Jung, Jaeeun, Park, Kunhyang, Lee, Moo-Seung, Kim, Mi-Young, Oh, Soo Jin, Hur, Keun, Hamamoto, Ryuji, Park, Doo-Sang, Kim, Dae-Soo, Son, Mi-Young, Cho, Hyun-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9038766/
https://www.ncbi.nlm.nih.gov/pubmed/34972816
http://dx.doi.org/10.1038/s41396-021-01119-1