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Patterns of amygdala region pathology in LATE-NC: subtypes that differ with regard to TDP-43 histopathology, genetic risk factors, and comorbid pathologies

Transactive response (TAR) DNA-binding protein 43 kDa (TDP-43) pathology is a hallmark of limbic-predominant age-related TDP-43 encephalopathy (LATE). The amygdala is affected early in the evolution of LATE neuropathologic change (LATE-NC), and heterogeneity of LATE-NC in amygdala has previously bee...

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Detalles Bibliográficos
Autores principales: Cykowski, Matthew D., Arumanayagam, Anithachristy S., Powell, Suzanne Z., Rivera, Andreana L., Abner, Erin L., Roman, Gustavo C., Masdeu, Joseph C., Nelson, Peter T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9038848/
https://www.ncbi.nlm.nih.gov/pubmed/35366087
http://dx.doi.org/10.1007/s00401-022-02416-5