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Immunoreactivity of humanized single-chain variable fragment against its functional epitope on domain 1 of CD147

Domain 1 of CD147 participates in matrix metalloproteinase (MMP) production and is a candidate for targeted therapy to prevent cancer invasion and metastasis. A functional mouse anti-CD147 monoclonal antibody, M6-1B9, was found to recognize domain 1 of CD147, and its respective mouse single-chain va...

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Detalles Bibliográficos
Autores principales: Intasai, Nutjeera, Rangnoi, Kuntalee, Yamabhai, Montarop, Pamonsupornwichit, Thanathat, Thongkum, Weeraya, Yasamut, Umpa, Chupradit, Koollawat, Takheaw, Nuchjira, Nimmanpipug, Piyarat, Tayapiwatana, Chatchai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9038914/
https://www.ncbi.nlm.nih.gov/pubmed/35468972
http://dx.doi.org/10.1038/s41598-022-10657-3