Weight-bearing activity impairs nuclear membrane and genome integrity via YAP activation in plantar melanoma

Acral melanoma commonly occurs in areas that are not exposed to much sunlight, such as the sole of the foot. Little is known about risk factors and mutational processes of plantar acral melanoma. Nuclear envelope rupture during interphase contributes to genome instability in cancer. Here, we show th...

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Detalles Bibliográficos
Autores principales: Seo, Jimyung, Kim, HyunSeok, Min, Kyoung Il, Kim, Changgon, Kwon, Yongsoo, Zheng, Zhenlong, Kim, Yusung, Park, Hyung-Soon, Ju, Young Seok, Roh, Mi Ryung, Chung, Kee Yang, Kim, Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9038926/
https://www.ncbi.nlm.nih.gov/pubmed/35468978
http://dx.doi.org/10.1038/s41467-022-29925-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9038926/
https://www.ncbi.nlm.nih.gov/pubmed/35468978
http://dx.doi.org/10.1038/s41467-022-29925-x

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