Cargando…
Weight-bearing activity impairs nuclear membrane and genome integrity via YAP activation in plantar melanoma
Acral melanoma commonly occurs in areas that are not exposed to much sunlight, such as the sole of the foot. Little is known about risk factors and mutational processes of plantar acral melanoma. Nuclear envelope rupture during interphase contributes to genome instability in cancer. Here, we show th...
| Autores principales: | , , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9038926/ https://www.ncbi.nlm.nih.gov/pubmed/35468978 http://dx.doi.org/10.1038/s41467-022-29925-x |