Reduced chromatin accessibility correlates with resistance to Notch activation

The Notch signalling pathway is a master regulator of cell fate transitions in development and disease. In the brain, Notch promotes neural stem cell (NSC) proliferation, regulates neuronal migration and maturation and can act as an oncogene or tumour suppressor. How NOTCH and its transcription fact...

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Detalles Bibliográficos
Autores principales: van den Ameele, Jelle, Krautz, Robert, Cheetham, Seth W., Donovan, Alex P. A., Llorà-Batlle, Oriol, Yakob, Rebecca, Brand, Andrea H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9039071/
https://www.ncbi.nlm.nih.gov/pubmed/35468895
http://dx.doi.org/10.1038/s41467-022-29834-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9039071/
https://www.ncbi.nlm.nih.gov/pubmed/35468895
http://dx.doi.org/10.1038/s41467-022-29834-z

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