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Reduced chromatin accessibility correlates with resistance to Notch activation
The Notch signalling pathway is a master regulator of cell fate transitions in development and disease. In the brain, Notch promotes neural stem cell (NSC) proliferation, regulates neuronal migration and maturation and can act as an oncogene or tumour suppressor. How NOTCH and its transcription fact...
Autores principales: | van den Ameele, Jelle, Krautz, Robert, Cheetham, Seth W., Donovan, Alex P. A., Llorà-Batlle, Oriol, Yakob, Rebecca, Brand, Andrea H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9039071/ https://www.ncbi.nlm.nih.gov/pubmed/35468895 http://dx.doi.org/10.1038/s41467-022-29834-z |
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